STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vsrProbable patch repair protein (dna mismatch endonuclease); May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. (154 aa)    
Predicted Functional Partners:
RSc3438
Probable site-specific dna methylase protein.
   
 0.953
mutL
Probable dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 
 0.860
pilA
Type 4 fimbrial pilin signal peptide protein; Belongs to the N-Me-Phe pilin family.
      
 0.618
RSc3252
Putative peptidase m, neutral zinc metallopeptidases, zinc-binding site; protein.
      
 0.618
RSc3437
Putative galactose mutarotase-like protein.
      
 0.618
gyrB
Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...]
       0.586
mexC
Probable multidrug efflux system protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
      
 0.531
brg11
Probable avrbs3 family type III effector protein; Exported into plant cells, where it is targeted to the nucleus and probably acts as a transcription factor. Binds DNA in a sequence-specific manner. May contribute to plant pathogenicity. Belongs to the transcription activator-like effector (TALE) family. RipTAL/RTL subfamily.
      
 0.523
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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