STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpCProbable methylcitrate synthase (citrate synthase 2) protein; Belongs to the citrate synthase family. (387 aa)    
Predicted Functional Partners:
prpD
Probable prpd protein.
 
 0.995
acnA2
Probable aconitate hydratase 1 transmembrane protein.
 
 0.994
prpB2
Putative carboxyvinyl-carboxyphosphonate phosphorylmutase protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 0.993
prpB1
Probable carboxyvinyl-carboxyphosphonate phosphorylmutase protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
 
 0.986
prpE
Propionyl-coenzyme a synthetase prpe protein.
  
 0.948
acsA
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) (acyl-activating enzyme) protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.948
RSp0651
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
 0.948
RSp1265
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
 0.948
mdh
Probable malate dehydrogenase. oxidoreductase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.931
RSc2536
Putative transmembrane aldehyde dehydrogenase oxidoreductase protein.
  
 0.931
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.