STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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RSp0197Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. (196 aa)    
Predicted Functional Partners:
aroC
Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.962
tyrA
Putative prephenate dehydrogenase oxidoreductase protein.
  
 
 0.934
pheA
Probable bifunctional protein: chorismate mutase and prephenate dehydratase.
  
 
 0.924
trpG
Probable panthranilate synthase component II (glutamine amido-transferase) protein.
  
 
 0.921
tyrB
Probable aromatic-amino-acid aminotransferase protein.
    
 0.919
trpE
Probable anthranilate synthase componentIprotein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate an [...]
  
 
 0.915
aroA
Probable 3-phosphoshikimate 1-carboxyvinyltransferase (epsp synthase) protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.907
RSc2512
Putative cyclohexadienyl dehydratase precursor signal peptide protein; Belongs to the bacterial solute-binding protein 3 family.
     
 0.903
pabB
Putative para-aminobenzoate synthetase componentIprotein.
  
 
 0.895
ispF
Probable cd00554, mecdp synthase (2-c-methyl-d-erythritol-2,4-cyclodiphosphate synthase) protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
     
 0.862
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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