STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSp0201Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. (808 aa)    
Predicted Functional Partners:
ilvH
Probable acetolactate synthase isozyme III (small subunit) protein.
  
 
 0.918
RSp0200
Probable aminotransferase class-III; oxidoreductase protein.
     
 0.814
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.733
gltB
Probable glutamate synthase (large subunit) oxidoreductase protein.
     
 0.604
maeB1
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 
 0.584
maeB2
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 
 0.584
RSc1806
Probable polyketide synthase protein.
  
 0.569
katE
Probable catalase hydroperoxidase hpII oxidoreductase protein; Belongs to the catalase family.
   
 0.549
iolD
Putative acetolactate synthase protein; Belongs to the TPP enzyme family.
     
  0.540
ilvG
Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family.
     
  0.540
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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