STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
treAProbable periplasmic alpha,alpha-trehalase signal peptide protein; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system. (551 aa)    
Predicted Functional Partners:
otsB
Probable trehalose-phosphatase protein; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.989
RSp0237
Putative 1,4-alpha-glucan branching enzyme protein.
  
 
 0.974
RSp0240
Putative glycosidase possibly involved in trehalose metabolism protein.
  
 
 0.931
glgE
Putative alpha-amylase-related protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
  
  
 0.788
glgB
Probable 1,4-alpha-glucan branching enzyme protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
  
 0.764
katE
Probable catalase hydroperoxidase hpII oxidoreductase protein; Belongs to the catalase family.
   
  
 0.723
RSp0278
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
       0.561
glk
Probable glucokinase (glucose kinase) protein; Belongs to the bacterial glucokinase family.
    
 0.531
otsA
Probable alpha,alpha-trehalose-phosphate synthase protein; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
 
  
 0.526
RSc1083
Putative galactose mutarotase-like protein.
   
 
  0.503
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (34%) [HD]