STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgBProbable fumarylacetoacetase (fumarylacetoacetate hydrolase) protein. (423 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
 0.995
nagL
Probable glutathione s-transferase protein.
 
 
 0.983
gstB
Probable glutathione s-transferase protein.
 
 0.933
phhA
Probable phenylalanine-4-hydroxylase (pah) (phe-4-monooxygenase). oxidoreductase protein.
 
  
 0.909
RSc0301
Fumarylacetoacetate (FAA) hydrolase; Putative 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) oxidoreductase protein.
     
 0.903
RSc0383
Fumarylpyruvate hydrolase; Probable 2-keto-4-pentenoate hydratase / 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) oxidoreductase protein.
     
 0.900
nagK
Putative isomerase-decarboxylase homolog protein.
     
 0.900
phhB
Putative pterin-4-alpha-carbinolamine dehydratase (phs)(4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin carbinolamine dehydratase) (pcd) protein.
 
  
 0.898
fumC
Probable fumarate hydratase class II (fumarase c) protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.837
sdhA
Putative succinate dehydrogenase (flavoprotein subunit) oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.827
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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