STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (448 aa)    
Predicted Functional Partners:
hpd
Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein.
 
 0.997
hmgB
Probable fumarylacetoacetase (fumarylacetoacetate hydrolase) protein.
  
 0.995
RSp1316
Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein.
 
 0.995
nagL
Probable glutathione s-transferase protein.
 
 
 0.994
RSp1400
Probable 4-hydroxyphenylpyruvate dioxygenase-related protein.
 
 0.991
phhA
Probable phenylalanine-4-hydroxylase (pah) (phe-4-monooxygenase). oxidoreductase protein.
 
  
 0.934
gstB
Probable glutathione s-transferase protein.
 
 
 0.919
RSp1347
Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein.
 
 
 0.915
phhB
Putative pterin-4-alpha-carbinolamine dehydratase (phs)(4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin carbinolamine dehydratase) (pcd) protein.
 
  
 0.843
tyrB
Probable aromatic-amino-acid aminotransferase protein.
  
  
 0.755
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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