STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmpFProbable acetaldehyde dehydrogenase oxidoreductase protein; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (306 aa)    
Predicted Functional Partners:
dmpG
Probable 4-hydroxy-2-oxovalerate aldolase protein; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 0.999
RSp0891
Putative hydratase/decarboxylase; protein.
  
 0.986
RSp0892
Putative hydratase/decarboxylase; protein.
 
  
 0.985
leuA1
2-isopropylmalate synthase 1; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.983
leuA2
2-isopropylmalate synthase 2; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.983
exaC
Putative nad+ dependent acetaldehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
    
 0.963
dmpI
Probable tautomerase protein; Belongs to the 4-oxalocrotonate tautomerase family.
 
   
 0.945
cmtC
Probable 2,3-dihydroxy-p-cumate-3,4-dioxygenase oxidoreductase protein.
 
   
 0.941
RSp0899
Probable hydratase/decarboxylase; protein.
 
  
 0.935
RSc2350
Probable aldehyde dehydrogenase oxidoreductase protein; Belongs to the aldehyde dehydrogenase family.
    
 0.933
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.