STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
epsEepsIpolysaccharide export inner membrane epse. transmembrane protein; Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May play a role in export of EPS I or its intermediates across the membranes (By similarity); To E.coli bicyclomycin resistance protein (BCR). (436 aa)    
Predicted Functional Partners:
epsD
Ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase. oxidoreductase protein; Probably involved in the synthesis of sugar components of EPS I, by converting NDP-N-acetyl-D-galactosamine into NDP-N-acetyl-D- galactosaminuronic acid.
  
  
 0.933
epsC
Udp-n-acetylglucosamine 2-epimerase (udp-glcnac-2-epimerase) protein; May be involved in synthesis of N-acetyltrideoxygalactose, a component of exopolysaccharide EPS I which functions as a virulence factor; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
  
  
 0.930
epsB
Putative tyrosine-protein kinase epsb (eps ipolysaccharide export epsb). transmembrane; Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the inner membrane or their polymerization (By similarity).
  
  
 0.917
epsF
epsIpolysaccharide export inner membrane epsf. transmembrane protein; Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May play a role in export of EPS I or its intermediates across the membranes (By similarity); To S.marcescens SfuB.
     
 0.831
rfbB
Probable dtdp-glucose 4,6-dehydratase protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.814
ugd
Probable udp-glucose 6-dehydrogenase (ugd) oxidoreductase protein.
  
  
 0.814
rfbC
Probable dtdp-4-dehydrorhamnose 3,5-epimerase protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.807
rfbA
Probable glucose-1-phosphate thymidylyltransferase protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.805
epsA
epsIpolysaccharide export outer membrane epsa precursor. transmembrane protein; Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. Belongs to the BexD/CtrA/VexA family.
  
  
 0.766
RSp1008
Probable glycosyl transferase transmembrane protein.
  
  
 0.731
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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