STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSp1347Probable 4-hydroxyphenylpyruvate dioxygenase oxidoreductase protein. (361 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.918
phhA
Probable phenylalanine-4-hydroxylase (pah) (phe-4-monooxygenase). oxidoreductase protein.
 
  
 0.883
hmgB
Probable fumarylacetoacetase (fumarylacetoacetate hydrolase) protein.
 
  
 0.813
gstB
Probable glutathione s-transferase protein.
 
  
 0.810
nagL
Probable glutathione s-transferase protein.
 
  
 0.805
RSc0301
Fumarylacetoacetate (FAA) hydrolase; Putative 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) oxidoreductase protein.
 
  
 0.794
RSp1345
Putative zn-dependent hydrolases protein.
 
   
 0.701
RSp1346
Hypothetical transmembrane protein.
  
   0.682
phhB
Putative pterin-4-alpha-carbinolamine dehydratase (phs)(4-alpha-hydroxy-tetrahydropterin dehydratase) (pterin carbinolamine dehydratase) (pcd) protein.
  
  
 0.605
icmF
Putative methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
     
 0.604
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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