STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSp1481Probable transmembrane protein. (698 aa)    
Predicted Functional Partners:
RSp1482
Putative outer membrane transmembrane protein.
     0.992
RSp1483
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
      0.942
RSp1480
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
      0.938
gyrA
Probable dna gyrase (subunit a)(type II topoisomerase) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simulta [...]
   
 
 0.778
parC
Probable dna topoisomerase iv (subunit a) protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
 
 0.778
phaZ
Probable poly[d(-)-3-hydroxybutyrate] depolymerase protein.
  
     0.470
RSc1443
Probable 2h phosphoesterase (2'-5' rna ligase) protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
  
     0.470
RSc1585
Putative galactose mutarotase-related protein.
  
     0.460
RSc1355
Hypothetical protein of unknown function upf0131.
  
     0.451
RSc3135
Hypothetical ferritin/ribonucleotide reductase-like; protein.
  
     0.443
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (22%) [HD]