STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSp1516Probable amino-acid dehydratase protein. (323 aa)    
Predicted Functional Partners:
RSp1515
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
 
 0.908
RSp1517
Hypothetical conserved protein; Miscellaneous; hypothetical/global homology.
 
     0.839
ilvD
Probable dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family.
  
 0.735
edd
Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 0.635
ilvH
Probable acetolactate synthase isozyme III (small subunit) protein.
  
  
 0.590
gltB
Probable glutamate synthase (large subunit) oxidoreductase protein.
  
 
 0.588
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.584
pabB
Putative para-aminobenzoate synthetase componentIprotein.
  
  
 0.569
thrC
Probable threonine synthase protein.
  
  
 0.514
RSp1518
Probable signal peptide protein.
       0.492
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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