STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zwfProbable glucose-6-phosphate 1-dehydrogenase oxidoreductase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)    
Predicted Functional Partners:
pgl
Probable 6-phosphogluconolactonase oxidoreductase protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.999
glk
Probable glucokinase (glucose kinase) protein; Belongs to the bacterial glucokinase family.
 
 0.995
edd
Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
  
 0.990
pgi
Probable glucose-6-phosphate isomerase (gpi) (phosphoglucoseisomerase) (pgi) (phosphohexose isomerase) (phi). transmembrane protein.
  
 
 0.976
gapA
Probable glyceraldehyde-3-phosphate dehydrogenase (gapdh). oxidoreductase protein; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
  
 0.930
fbaA
Probable fructose-bisphosphate aldolase protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.919
eno
Probable enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.916
tpiA
Probable triosephosphate isomerase (tim) (triose-phosphateisomerase) protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.908
eda
Probable bifunctional alkh protein (khg/kdpg aldolase): 4-hydroxy-2-oxoglutarate aldolase and 2-dehydro-3-deoxyphosphogluconate aldolase.
 
  
 0.902
ppsA
Probable phosphoenolpyruvate synthase protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.883
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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