| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0049 | RSp0183 | RSc0049 | RSp0183 | Probable 3-carboxymuconate cyclase protein. | Probable 3-carboxymuconate cyclase protein. | 0.919 |
| RSc0049 | edd | RSc0049 | RSp1560 | Probable 3-carboxymuconate cyclase protein. | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.900 |
| RSc0049 | pgl | RSc0049 | RSp1558 | Probable 3-carboxymuconate cyclase protein. | Probable 6-phosphogluconolactonase oxidoreductase protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.902 |
| RSc0049 | zwf | RSc0049 | RSp1559 | Probable 3-carboxymuconate cyclase protein. | Probable glucose-6-phosphate 1-dehydrogenase oxidoreductase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.914 |
| RSp0183 | RSc0049 | RSp0183 | RSc0049 | Probable 3-carboxymuconate cyclase protein. | Probable 3-carboxymuconate cyclase protein. | 0.919 |
| RSp0183 | edd | RSp0183 | RSp1560 | Probable 3-carboxymuconate cyclase protein. | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.900 |
| RSp0183 | pgl | RSp0183 | RSp1558 | Probable 3-carboxymuconate cyclase protein. | Probable 6-phosphogluconolactonase oxidoreductase protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.902 |
| RSp0183 | zwf | RSp0183 | RSp1559 | Probable 3-carboxymuconate cyclase protein. | Probable glucose-6-phosphate 1-dehydrogenase oxidoreductase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.914 |
| edd | RSc0049 | RSp1560 | RSc0049 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable 3-carboxymuconate cyclase protein. | 0.900 |
| edd | RSp0183 | RSp1560 | RSp0183 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable 3-carboxymuconate cyclase protein. | 0.900 |
| edd | eno | RSp1560 | RSc1129 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.463 |
| edd | gapA | RSp1560 | RSc2749 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable glyceraldehyde-3-phosphate dehydrogenase (gapdh). oxidoreductase protein; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.659 |
| edd | glk | RSp1560 | RSp1557 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable glucokinase (glucose kinase) protein; Belongs to the bacterial glucokinase family. | 0.938 |
| edd | pgi | RSp1560 | RSc1719 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable glucose-6-phosphate isomerase (gpi) (phosphoglucoseisomerase) (pgi) (phosphohexose isomerase) (phi). transmembrane protein. | 0.464 |
| edd | pgl | RSp1560 | RSp1558 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable 6-phosphogluconolactonase oxidoreductase protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. | 0.997 |
| edd | rpe | RSp1560 | RSc2879 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable ribulose-phosphate 3-epimerase protein; Belongs to the ribulose-phosphate 3-epimerase family. | 0.447 |
| edd | tal | RSp1560 | RSc1231 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.531 |
| edd | zwf | RSp1560 | RSp1559 | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | Probable glucose-6-phosphate 1-dehydrogenase oxidoreductase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.968 |
| eno | edd | RSc1129 | RSp1560 | Probable enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Probable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.463 |
| eno | gapA | RSc1129 | RSc2749 | Probable enolase (2-phosphoglycerate dehydratase) (2-phospho-d-glycerate hydro-lyase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Probable glyceraldehyde-3-phosphate dehydrogenase (gapdh). oxidoreductase protein; Catalyzes the oxidative phosphorylation of glyceraldehyde 3- phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG. | 0.990 |