STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eddProbable phosphogluconate dehydratase oxidoreductase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)    
Predicted Functional Partners:
eda
Probable bifunctional alkh protein (khg/kdpg aldolase): 4-hydroxy-2-oxoglutarate aldolase and 2-dehydro-3-deoxyphosphogluconate aldolase.
 
 0.998
pgl
Probable 6-phosphogluconolactonase oxidoreductase protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 0.997
zwf
Probable glucose-6-phosphate 1-dehydrogenase oxidoreductase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.990
glk
Probable glucokinase (glucose kinase) protein; Belongs to the bacterial glucokinase family.
 
  
 0.942
gntK
Probable thermoresistant gluconokinase (gluconate kinase 2) protein.
  
 
 0.925
RSp0946
Putative gluconate kinase protein.
  
 
 0.925
RSp1184
Putative fructokinase-like protein (sugar kinase).
    
 0.909
gltB
Probable glutamate synthase (large subunit) oxidoreductase protein.
  
  
 0.838
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.836
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.776
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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