Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III beta chain; COG0592; expression validated by proteogenomic mapping: 18 unique peptides covering 44.2% of sequence. (369 aa)    
Predicted Functional Partners:
holB
DNA polymerase III subunit delta; COG0470; expression validated by proteogenomic mapping: 1 unique peptides covering 6.3% of sequence.
 
 0.998
dnaX
DNA polymerase III subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.992
polA
DNA polymerase I; COG0258; expression validated by proteogenomic mapping: 13 unique peptides covering 33.9% of sequence.
  
 0.992
holA
DNA polymerase III delta subunit; COG1466; expression validated by proteogenomic mapping: 1 unique peptides covering 3.9% of sequence.
 
 
 0.991
dnaE-2
DNA polymerase III alpha subunit; COG0587; expression validated by proteogenomic mapping: 15 unique peptides covering 21.4% of sequence.
    
 0.989
dnaE
DNA polymerase III alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.965
mucB
DNA-damage repair protein; COG0389; expression validated by proteogenomic mapping: 1 unique peptides covering 2.7% of sequence.
  
 0.963
snf2
Swf/snf family helicase-like protein; COG0553; expression validated by proteogenomic mapping: 17 unique peptides covering 20.7% of sequence.
  
 0.946
recA
Recombination protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.910
rnhB-2
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
 
 0.890
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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