Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
lplALipoate-protein ligase; COG0095; expression validated by proteogenomic mapping: 22 unique peptides covering 63.3% of sequence. (327 aa)    
Predicted Functional Partners:
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
  
 0.877
MMOB0590
Expressed protein; Expression validated by proteogenomic mapping: 3 unique peptides covering 30.2% of sequence.
       0.813
pdhC
Pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 78 unique peptides covering 80.1% of sequence.
  
 0.777
pdhC-2
Truncated pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 29 unique peptides covering 69.5% of sequence.
  
 0.777
nox
NADH oxidase; COG0446; expression validated by proteogenomic mapping: 70 unique peptides covering 81% of sequence.
      0.711
pdhB
Pyruvate dehydrogenase E1 component beta subunit; COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence.
 
  
 0.686
MMOB0600
Expressed protein; Expression validated by proteogenomic mapping: 3 unique peptides covering 9.8% of sequence.
       0.545
pdhD
Dihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex); COG1249; expression validated by proteogenomic mapping: 25 unique peptides covering 40% of sequence.
  
  
 0.504
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
  
 0.427
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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