Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
trxA-2Thioredoxin; COG3118; expression validated by proteogenomic mapping: 8 unique peptides covering 78.2% of sequence; Belongs to the thioredoxin family. (101 aa)    
Predicted Functional Partners:
trxB
Thioredoxin reductase; COG0492; expression validated by proteogenomic mapping: 51 unique peptides covering 78.5% of sequence.
  
 
 0.818
nrdA
Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.703
proRS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
   
   0.627
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
  
 
 0.606
tufA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.549
trxA
Thioredoxin; COG3118; expression validated by proteogenomic mapping: 13 unique peptides covering 76% of sequence; Belongs to the thioredoxin family.
      
0.511
pmsR-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.509
gapA
Glyceraldehyde 3-phosphate dehydrogenase; COG0057; expression validated by proteogenomic mapping: 74 unique peptides covering 96.5% of sequence; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.478
nusG
Transcription antitermination factor; Participates in transcription elongation, termination and antitermination.
  
   0.462
MMOB1410
COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 5 unique peptides covering 19% of sequence.
  
    0.447
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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