STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhDDihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex); COG1249; expression validated by proteogenomic mapping: 25 unique peptides covering 40% of sequence. (473 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component beta subunit; COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence.
  
 0.995
pmsR-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.993
pdhC
Pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 78 unique peptides covering 80.1% of sequence.
  
 0.982
pdhC-2
Truncated pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 29 unique peptides covering 69.5% of sequence.
  
 0.982
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.962
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
 
0.961
lplA
Lipoate-protein ligase; COG0095; expression validated by proteogenomic mapping: 22 unique peptides covering 63.3% of sequence.
  
 
 0.921
prsA
Phosphoribosylpyrophosphate synthetase; COG0462; expression validated by proteogenomic mapping: 32 unique peptides covering 63% of sequence.
   
 0.906
pepA
Leucyl aminopeptidase; COG0260; expression validated by proteogenomic mapping: 36 unique peptides covering 64.7% of sequence; Belongs to the peptidase M17 family.
  
 
 0.787
MMOB5580
Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence.
  
 0.683
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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