Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxBThioredoxin reductase; COG0492; expression validated by proteogenomic mapping: 51 unique peptides covering 78.5% of sequence. (311 aa)    
Predicted Functional Partners:
pmsR-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.919
nifS
Aminotransferase protein S homolog; COG0520; expression validated by proteogenomic mapping: 17 unique peptides covering 42.4% of sequence.
  
 
  0.912
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.865
trxA-3
Thioredoxin; COG0526; expression validated by proteogenomic mapping: 9 unique peptides covering 70.7% of sequence.
  
 
 0.838
ptsK
Hpr kinase; COG1493; expression validated by proteogenomic mapping: 15 unique peptides covering 48.4% of sequence; Belongs to the HPrK/P family.
     
 0.835
trxA
Thioredoxin; COG3118; expression validated by proteogenomic mapping: 13 unique peptides covering 76% of sequence; Belongs to the thioredoxin family.
  
 
 0.818
trxA-2
Thioredoxin; COG3118; expression validated by proteogenomic mapping: 8 unique peptides covering 78.2% of sequence; Belongs to the thioredoxin family.
  
 
 0.818
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.813
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
  
 
 0.619
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
    0.551
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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