Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemKProtoporphyrinogen oxidase; COG2890; expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence. (236 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.994
rpiB
Ribose 5-phosphate isomerase; COG0698; expression validated by proteogenomic mapping: 17 unique peptides covering 70.9% of sequence.
      0.772
metK
S-adenosylmethionine synthetase; COG0192; expression validated by proteogenomic mapping: 23 unique peptides covering 50% of sequence; Belongs to the AdoMet synthase family.
     
 0.677
MMOB1910
Conserved expressed protein; COG0217; expression validated by proteogenomic mapping: 12 unique peptides covering 34.4% of sequence.
     
 0.579
galE
Udp-glucose 4-epimerase; COG1087; expression validated by proteogenomic mapping: 26 unique peptides covering 48.5% of sequence; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
       0.563
ksgA
Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.561
nadE
NH(3)-dependent NAD(+) synthetase; COG0171; expression validated by proteogenomic mapping: 6 unique peptides covering 20.4% of sequence.
     
 0.555
atpE
ATP synthase c chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
   0.524
atpH
ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
  
   0.523
atpG
ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
  
   0.514
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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