prfA protein (Mycoplasma mobile) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

prfA

Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (358 aa)

Predicted Functional Partners:

hemK

0.994

rplC

0.900

rpmE

0.893

rplI

0.888

rpsF

0.888

rplQ

0.888

rplM

0.887

rpmA

0.887

rpsK

0.883

rplS

0.883

Your Current Organism:

Mycoplasma mobile

NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hemK	prfA	MMOB1890	MMOB1900	Protoporphyrinogen oxidase; COG2890; expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence.	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	0.994
prfA	hemK	MMOB1900	MMOB1890	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Protoporphyrinogen oxidase; COG2890; expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence.	0.994
prfA	rplC	MMOB1900	MMOB2350	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.900
prfA	rplI	MMOB1900	MMOB1720	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l9; Binds to the 23S rRNA.	0.888
prfA	rplM	MMOB1900	MMOB2290	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.887
prfA	rplQ	MMOB1900	MMOB2620	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l17; COG0203; expression validated by proteogenomic mapping: 8 unique peptides covering 47.5% of sequence.	0.888
prfA	rplS	MMOB1900	MMOB4280	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.883
prfA	rpmA	MMOB1900	MMOB3050	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	50S ribosomal protein l27; COG0211; expression validated by proteogenomic mapping: 9 unique peptides covering 57.6% of sequence; Belongs to the bacterial ribosomal protein bL27 family.	0.887
prfA	rpmE	MMOB1900	MMOB1280	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein l31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.	0.893
prfA	rpsF	MMOB1900	MMOB2270	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	30S ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA.	0.888
prfA	rpsK	MMOB1900	MMOB2600	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	30S ribosomal protein s11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.883
rplC	prfA	MMOB2350	MMOB1900	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	0.900
rplC	rplI	MMOB2350	MMOB1720	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein l9; Binds to the 23S rRNA.	0.992
rplC	rplM	MMOB2350	MMOB2290	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.998
rplC	rplQ	MMOB2350	MMOB2620	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein l17; COG0203; expression validated by proteogenomic mapping: 8 unique peptides covering 47.5% of sequence.	0.996
rplC	rplS	MMOB2350	MMOB4280	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein l19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.988
rplC	rpmA	MMOB2350	MMOB3050	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	50S ribosomal protein l27; COG0211; expression validated by proteogenomic mapping: 9 unique peptides covering 57.6% of sequence; Belongs to the bacterial ribosomal protein bL27 family.	0.992
rplC	rpmE	MMOB2350	MMOB1280	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	Ribosomal protein l31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.	0.910
rplC	rpsF	MMOB2350	MMOB2270	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	30S ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA.	0.991
rplC	rpsK	MMOB2350	MMOB2600	50S ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	30S ribosomal protein s11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.995

page 1 of 5

Server load: medium (54%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About