STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligNAD(+)-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (671 aa)    
Predicted Functional Partners:
MMOB1960
Unspecified ABC transporter ATP-binding subunit; COG1131; expression validated by proteogenomic mapping: 8 unique peptides covering 22.9% of sequence.
       0.788
MMOB1970
Similar to a M. penetrans protein; expression validated by proteogenomic mapping: 1 unique peptides covering 3.4% of sequence.
       0.776
leuS
leucyl-tRNA synthetase; COG0495; expression validated by proteogenomic mapping: 18 unique peptides covering 37.5% of sequence.
   
 
 0.758
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.679
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.513
pcrA1
ATP-dependent DNA helicase; COG0210; expression validated by proteogenomic mapping: 7 unique peptides covering 14% of sequence.
  
  
 0.510
pcrA2
ATP-dependent DNA helicase; COG0210; expression validated by proteogenomic mapping: 32 unique peptides covering 44.1% of sequence.
  
  
 0.510
pheT
phenylalanyl-tRNA synthetase beta chain; COG0072; expression validated by proteogenomic mapping: 17 unique peptides covering 31.3% of sequence; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.504
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
  
 
 0.500
pepF
Oligoendopeptidase f; COG1164; expression validated by proteogenomic mapping: 36 unique peptides covering 49.8% of sequence.
       0.498
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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