Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
glpQGlycerophosphoryl diester phosphodiesterase; COG0584; expression validated by proteogenomic mapping: 2 unique peptides covering 11.4% of sequence. (236 aa)    
Predicted Functional Partners:
MMOB2040
Unspecified permease; Major facilitator superfamily; COG0477; expression validated by proteogenomic mapping: 1 unique peptides covering 3.3% of sequence.
 
    0.855
gap1
Amino acid permease; COG0531; expression validated by proteogenomic mapping: 4 unique peptides covering 10.2% of sequence.
  
    0.643
tufA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
  
 0.617
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.611
glpF
Glycerol uptake facilitator protein; COG0580; expression validated by proteogenomic mapping: 1 unique peptides covering 4.3% of sequence; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.593
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.585
pgsA
Phosphatidylglycerophosphate synthase; COG0558; expression validated by proteogenomic mapping: 1 unique peptides covering 5.4% of sequence; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.573
malC
Maltodextrin ABC transporter permease protein; COG1175; expression validated by proteogenomic mapping: 1 unique peptides covering 3.7% of sequence.
  
  
 0.539
pstA
Phosphate ABC transporter permease protein; COG0581; COG0573; expression not validated.
  
  
 0.536
gyrB
DNA gyrase subunit b; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.464
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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