Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metKS-adenosylmethionine synthetase; COG0192; expression validated by proteogenomic mapping: 23 unique peptides covering 50% of sequence; Belongs to the AdoMet synthase family. (386 aa)    
Predicted Functional Partners:
wcaG
NAD-dependent nucleoside-diphosphate-sugar epimerase; COG0451; expression validated by proteogenomic mapping: 48 unique peptides covering 79.4% of sequence.
   
 0.947
MMOB3070
Expressed protein; Expression validated by proteogenomic mapping: 4 unique peptides covering 9.3% of sequence.
       0.778
MMOB3060
Expressed protein; Expression validated by proteogenomic mapping: 6 unique peptides covering 17.6% of sequence.
       0.773
MMOB3080
Expressed protein; Expression validated by proteogenomic mapping: 9 unique peptides covering 38.8% of sequence.
       0.773
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
 0.726
MMOB3100
Expressed protein; Expression validated by proteogenomic mapping: 9 unique peptides covering 18.1% of sequence.
       0.718
potB
Spermidine/putrescine ABC transporter permease protein; COG1176; expression not validated.
     
 0.709
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.690
mscL
Large-conductance mechanosensitive channel; COG1970; expression validated by proteogenomic mapping: 6 unique peptides covering 23.2% of sequence.
  
    0.678
hemK
Protoporphyrinogen oxidase; COG2890; expression validated by proteogenomic mapping: 2 unique peptides covering 5.5% of sequence.
     
 0.677
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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