STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (325 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; COG0166; expression validated by proteogenomic mapping: 41 unique peptides covering 65.1% of sequence.
  
 0.993
pyk
Pyruvate kinase; COG0469; expression validated by proteogenomic mapping: 72 unique peptides covering 78.9% of sequence; Belongs to the pyruvate kinase family.
  
 
 0.984
fba
Fructose-bisphosphate aldolase; COG0191; expression validated by proteogenomic mapping: 45 unique peptides covering 85.2% of sequence.
  
 
 0.972
tktA
Transketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family.
  
 
 0.942
manA
Mannose-6-phosphate isomerase; COG1482; expression validated by proteogenomic mapping: 15 unique peptides covering 43.3% of sequence.
    
 0.916
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.907
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.877
gapA
Glyceraldehyde 3-phosphate dehydrogenase; COG0057; expression validated by proteogenomic mapping: 74 unique peptides covering 96.5% of sequence; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.866
pgk-2
Phosphoglycerate kinase; COG0126; expression validated by proteogenomic mapping: 74 unique peptides covering 76.3% of sequence; Belongs to the phosphoglycerate kinase family.
  
  
 0.704
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase; COG0240; expression validated by proteogenomic mapping: 17 unique peptides covering 54.7% of sequence; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.587
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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