node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdd | era | MMOB3470 | MMOB3460 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.941 |
era | cdd | MMOB3460 | MMOB3470 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.941 |
era | ksgA | MMOB3460 | MMOB5640 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.955 |
era | rpsB | MMOB3460 | MMOB1760 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s2; COG0052; expression validated by proteogenomic mapping: 52 unique peptides covering 72.3% of sequence; Belongs to the universal ribosomal protein uS2 family. | 0.931 |
era | rpsE | MMOB3460 | MMOB2520 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.941 |
era | rpsF | MMOB3460 | MMOB2270 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA. | 0.985 |
era | rpsG | MMOB3460 | MMOB3680 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.983 |
era | rpsI | MMOB3460 | MMOB2300 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s9; COG0103; expression validated by proteogenomic mapping: 12 unique peptides covering 46.9% of sequence; Belongs to the universal ribosomal protein uS9 family. | 0.977 |
era | rpsJ | MMOB3460 | MMOB2340 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.951 |
era | rpsO | MMOB3460 | MMOB4690 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.937 |
era | rpsP | MMOB3460 | MMOB4300 | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein s16; COG0228; expression validated by proteogenomic mapping: 7 unique peptides covering 56.3% of sequence; Belongs to the bacterial ribosomal protein bS16 family. | 0.985 |
ksgA | era | MMOB5640 | MMOB3460 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | GTP-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.955 |
ksgA | rpsB | MMOB5640 | MMOB1760 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s2; COG0052; expression validated by proteogenomic mapping: 52 unique peptides covering 72.3% of sequence; Belongs to the universal ribosomal protein uS2 family. | 0.980 |
ksgA | rpsE | MMOB5640 | MMOB2520 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.978 |
ksgA | rpsF | MMOB5640 | MMOB2270 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s6; Binds together with S18 to 16S ribosomal RNA. | 0.963 |
ksgA | rpsG | MMOB5640 | MMOB3680 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.982 |
ksgA | rpsI | MMOB5640 | MMOB2300 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s9; COG0103; expression validated by proteogenomic mapping: 12 unique peptides covering 46.9% of sequence; Belongs to the universal ribosomal protein uS9 family. | 0.966 |
ksgA | rpsJ | MMOB5640 | MMOB2340 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.983 |
ksgA | rpsO | MMOB5640 | MMOB4690 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.978 |
ksgA | rpsP | MMOB5640 | MMOB4300 | Dimethyladenosine transferase rRNA modification enzyme; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 30S ribosomal protein s16; COG0228; expression validated by proteogenomic mapping: 7 unique peptides covering 56.3% of sequence; Belongs to the bacterial ribosomal protein bS16 family. | 0.955 |