| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruA | glpK | MMOB6060 | MMOB2940 | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.539 |
| fruA | glpR | MMOB6060 | MMOB4180 | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | 0.816 |
| fruA | ptsI | MMOB6060 | MMOB0610 | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.790 |
| fruA | tpiA | MMOB6060 | MMOB4190 | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.587 |
| glpK | fruA | MMOB2940 | MMOB6060 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | 0.539 |
| glpK | glpR | MMOB2940 | MMOB4180 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | 0.468 |
| glpK | tpiA | MMOB2940 | MMOB4190 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.404 |
| glpR | fruA | MMOB4180 | MMOB6060 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | 0.816 |
| glpR | glpK | MMOB4180 | MMOB2940 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.468 |
| glpR | obg | MMOB4180 | MMOB4220 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.417 |
| glpR | ptsI | MMOB4180 | MMOB0610 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | 0.414 |
| glpR | tpiA | MMOB4180 | MMOB4190 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.604 |
| glpR | wcaA-2 | MMOB4180 | MMOB4210 | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | Putative glycosyltransferase; COG0463; expression validated by proteogenomic mapping: 6 unique peptides covering 18.4% of sequence. | 0.429 |
| obg | glpR | MMOB4220 | MMOB4180 | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | 0.417 |
| obg | tpiA | MMOB4220 | MMOB4190 | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.646 |
| obg | wcaA-2 | MMOB4220 | MMOB4210 | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Putative glycosyltransferase; COG0463; expression validated by proteogenomic mapping: 6 unique peptides covering 18.4% of sequence. | 0.773 |
| ptsI | fruA | MMOB0610 | MMOB6060 | Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | 0.790 |
| ptsI | glpR | MMOB0610 | MMOB4180 | Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | deoR-family transcriptional repressor of sugar metabolism; COG1349; expression validated by proteogenomic mapping: 13 unique peptides covering 45.9% of sequence. | 0.414 |
| ptsI | tpiA | MMOB0610 | MMOB4190 | Phosphoenolpyruvate-protein phosphotransferase enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.407 |
| tpiA | fruA | MMOB4190 | MMOB6060 | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence. | 0.587 |