| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMOB3430 | cls | MMOB3430 | MMOB4560 | Truncated late competance locus-related protein; Possible lipoprotein; COG2333; expression not validated. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.569 |
| MMOB3430 | gmk | MMOB3430 | MMOB5570 | Truncated late competance locus-related protein; Possible lipoprotein; COG2333; expression not validated. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.466 |
| MMOB4540 | MMOB4550 | MMOB4540 | MMOB4550 | Expressed protein; Expression validated by proteogenomic mapping: 51 unique peptides covering 67% of sequence. | Expressed protein; COG1624; expression validated by proteogenomic mapping: 6 unique peptides covering 23.1% of sequence. | 0.787 |
| MMOB4540 | cls | MMOB4540 | MMOB4560 | Expressed protein; Expression validated by proteogenomic mapping: 51 unique peptides covering 67% of sequence. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.740 |
| MMOB4550 | MMOB4540 | MMOB4550 | MMOB4540 | Expressed protein; COG1624; expression validated by proteogenomic mapping: 6 unique peptides covering 23.1% of sequence. | Expressed protein; Expression validated by proteogenomic mapping: 51 unique peptides covering 67% of sequence. | 0.787 |
| MMOB4550 | cls | MMOB4550 | MMOB4560 | Expressed protein; COG1624; expression validated by proteogenomic mapping: 6 unique peptides covering 23.1% of sequence. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.490 |
| cls | MMOB3430 | MMOB4560 | MMOB3430 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Truncated late competance locus-related protein; Possible lipoprotein; COG2333; expression not validated. | 0.569 |
| cls | MMOB4540 | MMOB4560 | MMOB4540 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Expressed protein; Expression validated by proteogenomic mapping: 51 unique peptides covering 67% of sequence. | 0.740 |
| cls | MMOB4550 | MMOB4560 | MMOB4550 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Expressed protein; COG1624; expression validated by proteogenomic mapping: 6 unique peptides covering 23.1% of sequence. | 0.490 |
| cls | glpQ | MMOB4560 | MMOB2050 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Glycerophosphoryl diester phosphodiesterase; COG0584; expression validated by proteogenomic mapping: 2 unique peptides covering 11.4% of sequence. | 0.417 |
| cls | glyA | MMOB4560 | MMOB4710 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.557 |
| cls | gmk | MMOB4560 | MMOB5570 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.648 |
| cls | obg | MMOB4560 | MMOB4220 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.419 |
| cls | plsC | MMOB4560 | MMOB4780 | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 1-acyl-sn-glycerol-3-phosphate acyltransferase; COG0204; expression validated by proteogenomic mapping: 11 unique peptides covering 33.3% of sequence. | 0.473 |
| glpQ | cls | MMOB2050 | MMOB4560 | Glycerophosphoryl diester phosphodiesterase; COG0584; expression validated by proteogenomic mapping: 2 unique peptides covering 11.4% of sequence. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.417 |
| glyA | cls | MMOB4710 | MMOB4560 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.557 |
| glyA | gmk | MMOB4710 | MMOB5570 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.548 |
| gmk | MMOB3430 | MMOB5570 | MMOB3430 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Truncated late competance locus-related protein; Possible lipoprotein; COG2333; expression not validated. | 0.466 |
| gmk | cls | MMOB5570 | MMOB4560 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. | 0.648 |
| gmk | glyA | MMOB5570 | MMOB4710 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.548 |