| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMOB4670 | MMOB4700 | MMOB4670 | MMOB4700 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | Hypothetical protein; Expression not validated. | 0.496 |
| MMOB4670 | glyA | MMOB4670 | MMOB4710 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.455 |
| MMOB4670 | hsp33 | MMOB4670 | MMOB4720 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | Hsp33 disulfide bond chaperone; COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence. | 0.449 |
| MMOB4670 | ribF | MMOB4670 | MMOB4680 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | FAD synthase (riboflavin kinase/biosynthesis protein); COG0196; expression validated by proteogenomic mapping: 3 unique peptides covering 13.5% of sequence. | 0.830 |
| MMOB4670 | rpsO | MMOB4670 | MMOB4690 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | 30S ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.762 |
| MMOB4670 | truB | MMOB4670 | MMOB4660 | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.823 |
| MMOB4700 | MMOB4670 | MMOB4700 | MMOB4670 | Hypothetical protein; Expression not validated. | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | 0.496 |
| MMOB4700 | glyA | MMOB4700 | MMOB4710 | Hypothetical protein; Expression not validated. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.689 |
| MMOB4700 | hsp33 | MMOB4700 | MMOB4720 | Hypothetical protein; Expression not validated. | Hsp33 disulfide bond chaperone; COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence. | 0.689 |
| MMOB4700 | ribF | MMOB4700 | MMOB4680 | Hypothetical protein; Expression not validated. | FAD synthase (riboflavin kinase/biosynthesis protein); COG0196; expression validated by proteogenomic mapping: 3 unique peptides covering 13.5% of sequence. | 0.496 |
| MMOB4700 | rpsO | MMOB4700 | MMOB4690 | Hypothetical protein; Expression not validated. | 30S ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.568 |
| MMOB4700 | truB | MMOB4700 | MMOB4660 | Hypothetical protein; Expression not validated. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.496 |
| glyA | MMOB4670 | MMOB4710 | MMOB4670 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | 0.455 |
| glyA | MMOB4700 | MMOB4710 | MMOB4700 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hypothetical protein; Expression not validated. | 0.689 |
| glyA | hsp33 | MMOB4710 | MMOB4720 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hsp33 disulfide bond chaperone; COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence. | 0.774 |
| glyA | ribF | MMOB4710 | MMOB4680 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | FAD synthase (riboflavin kinase/biosynthesis protein); COG0196; expression validated by proteogenomic mapping: 3 unique peptides covering 13.5% of sequence. | 0.474 |
| glyA | rpsO | MMOB4710 | MMOB4690 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 30S ribosomal protein s15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.644 |
| glyA | truB | MMOB4710 | MMOB4660 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.493 |
| hsp33 | MMOB4670 | MMOB4720 | MMOB4670 | Hsp33 disulfide bond chaperone; COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence. | COF family HAD hydrolase protein; COG0561; expression validated by proteogenomic mapping: 8 unique peptides covering 27.4% of sequence. | 0.449 |
| hsp33 | MMOB4700 | MMOB4720 | MMOB4700 | Hsp33 disulfide bond chaperone; COG1281; expression validated by proteogenomic mapping: 7 unique peptides covering 28.3% of sequence. | Hypothetical protein; Expression not validated. | 0.689 |