Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
derPredicted GTPase protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (432 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; COG0283; expression validated by proteogenomic mapping: 15 unique peptides covering 30% of sequence.
 
  
 0.993
gpsA
NAD-dependent glycerol-3-phosphate dehydrogenase; COG0240; expression validated by proteogenomic mapping: 17 unique peptides covering 54.7% of sequence; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.985
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.922
rplA
50S ribosomal protein l1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.915
rplN
50S ribosomal protein l14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.880
MMOB1190
Putative GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
  
 
 0.874
rplT
50S ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
    
 
 0.873
rplR
50S ribosomal protein l18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.871
rpmH
50S ribosomal protein l34; COG0230; expression validated by proteogenomic mapping: 2 unique peptides covering 21.3% of sequence; Belongs to the bacterial ribosomal protein bL34 family.
  
 
 0.870
rpmA
50S ribosomal protein l27; COG0211; expression validated by proteogenomic mapping: 9 unique peptides covering 57.6% of sequence; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.866
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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