| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MMOB5580 | dnaJ | MMOB5580 | MMOB4850 | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.837 |
| MMOB5580 | dnaK | MMOB5580 | MMOB1130 | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.741 |
| MMOB5580 | glpF | MMOB5580 | MMOB2930 | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | Glycerol uptake facilitator protein; COG0580; expression validated by proteogenomic mapping: 1 unique peptides covering 4.3% of sequence; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.810 |
| MMOB5580 | pmsR-2 | MMOB5580 | MMOB4950 | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.848 |
| MMOB5580 | thdF | MMOB5580 | MMOB5620 | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.466 |
| clpB | dnaJ | MMOB3650 | MMOB4850 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.868 |
| clpB | dnaK | MMOB3650 | MMOB1130 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.992 |
| clpB | glpF | MMOB3650 | MMOB2930 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | Glycerol uptake facilitator protein; COG0580; expression validated by proteogenomic mapping: 1 unique peptides covering 4.3% of sequence; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.650 |
| clpB | grpE | MMOB3650 | MMOB1120 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.921 |
| clpB | pmsR-2 | MMOB3650 | MMOB4950 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.666 |
| clpB | rpsG | MMOB3650 | MMOB3680 | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | 30S ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.476 |
| deaD | dnaJ | MMOB2800 | MMOB4850 | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.844 |
| deaD | dnaK | MMOB2800 | MMOB1130 | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.729 |
| deaD | pmsR-2 | MMOB2800 | MMOB4950 | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.612 |
| deaD | rplQ | MMOB2800 | MMOB2620 | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | 50S ribosomal protein l17; COG0203; expression validated by proteogenomic mapping: 8 unique peptides covering 47.5% of sequence. | 0.786 |
| deaD | thdF | MMOB2800 | MMOB5620 | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.424 |
| dnaJ | MMOB5580 | MMOB4850 | MMOB5580 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence. | 0.837 |
| dnaJ | clpB | MMOB4850 | MMOB3650 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | ATP-dependent Clp protease, ATPase subunit; COG0542; expression validated by proteogenomic mapping: 52 unique peptides covering 57.4% of sequence; Belongs to the ClpA/ClpB family. | 0.868 |
| dnaJ | deaD | MMOB4850 | MMOB2800 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | DEAD-box ATP-dependent RNA helicase; COG0513; expression validated by proteogenomic mapping: 27 unique peptides covering 34.8% of sequence. | 0.844 |
| dnaJ | dnaK | MMOB4850 | MMOB1130 | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
