Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
manAMannose-6-phosphate isomerase; COG1482; expression validated by proteogenomic mapping: 15 unique peptides covering 43.3% of sequence. (319 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; COG0166; expression validated by proteogenomic mapping: 41 unique peptides covering 65.1% of sequence.
  
 
 0.942
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.919
glcK
Putative sugar binding signalling protein; Similar to sugar-related transcriptional regulator but lacks DNA-binding domain; COG1940; COG0837; expression validated by proteogenomic mapping: 28 unique peptides covering 58% of sequence.
 
  
 0.885
manB-3
Phosphomannomutase; COG1109; expression validated by proteogenomic mapping: 3 unique peptides covering 5.2% of sequence.
  
 
 0.787
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.767
fruA
PTS system fructose specific IIABC component; COG1299; expression validated by proteogenomic mapping: 18 unique peptides covering 28.6% of sequence.
  
  
 0.698
manB
Phosphoglucomutase/phosphomannomutase; COG1109; expression validated by proteogenomic mapping: 14 unique peptides covering 19% of sequence.
  
 
 0.604
ffh
Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
       0.553
rsmI
Putative SAM-dependent methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.490
holB
DNA polymerase III subunit delta; COG0470; expression validated by proteogenomic mapping: 1 unique peptides covering 6.3% of sequence.
       0.486
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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