Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tktATransketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family. (613 aa)    
Predicted Functional Partners:
rpe
Ribulose-5-phosphate 3-epimerase; COG0036; expression validated by proteogenomic mapping: 4 unique peptides covering 32.6% of sequence.
 
 0.979
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.974
gapA
Glyceraldehyde 3-phosphate dehydrogenase; COG0057; expression validated by proteogenomic mapping: 74 unique peptides covering 96.5% of sequence; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.964
fba
Fructose-bisphosphate aldolase; COG0191; expression validated by proteogenomic mapping: 45 unique peptides covering 85.2% of sequence.
  
 0.963
pgi
Glucose-6-phosphate isomerase; COG0166; expression validated by proteogenomic mapping: 41 unique peptides covering 65.1% of sequence.
  
 0.963
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.945
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 0.944
prsA
Phosphoribosylpyrophosphate synthetase; COG0462; expression validated by proteogenomic mapping: 32 unique peptides covering 63% of sequence.
   
 
 0.944
rpiB
Ribose 5-phosphate isomerase; COG0698; expression validated by proteogenomic mapping: 17 unique peptides covering 70.9% of sequence.
  
 
 0.941
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.936
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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