Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prsAPhosphoribosylpyrophosphate synthetase; COG0462; expression validated by proteogenomic mapping: 32 unique peptides covering 63% of sequence. (332 aa)    
Predicted Functional Partners:
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
  
 0.987
pdhB
Pyruvate dehydrogenase E1 component beta subunit; COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence.
  
 0.969
tktA
Transketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family.
   
 
 0.944
rpiB
Ribose 5-phosphate isomerase; COG0698; expression validated by proteogenomic mapping: 17 unique peptides covering 70.9% of sequence.
  
 
 0.939
manB-2
Phosphomannomutase; COG1109; expression validated by proteogenomic mapping: 40 unique peptides covering 63.4% of sequence.
  
 0.922
manB-3
Phosphomannomutase; COG1109; expression validated by proteogenomic mapping: 3 unique peptides covering 5.2% of sequence.
  
 0.922
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
    
 0.920
pdhD
Dihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex); COG1249; expression validated by proteogenomic mapping: 25 unique peptides covering 40% of sequence.
   
 0.871
MMOB5580
Phosphoprotein ser/thr phosphatase; COG0631; expression validated by proteogenomic mapping: 24 unique peptides covering 63.1% of sequence.
   
 0.834
pdhC
Pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 78 unique peptides covering 80.1% of sequence.
  
 0.827
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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