STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioF8-amino-7-oxononanoate synthase; COG0156; expression validated by proteogenomic mapping: 63 unique peptides covering 80.7% of sequence. (398 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.942
wcaG
NAD-dependent nucleoside-diphosphate-sugar epimerase; COG0451; expression validated by proteogenomic mapping: 48 unique peptides covering 79.4% of sequence.
  
 
 0.887
coaE
Hypothetical dephospho-CoA kinase; COG0237; expression not validated.
  
  
 0.662
coaD
Putative phosphopantetheine adenylyltransferase; COG0669; expression validated by proteogenomic mapping: 4 unique peptides covering 32.4% of sequence.
     
 0.548
ribA
Riboflavin biosynthesis protein; COG0807; expression validated by proteogenomic mapping: 9 unique peptides covering 20.4% of sequence.
     
 0.476
acpP
Acyl carrier protein; COG0236; expression validated by proteogenomic mapping: 7 unique peptides covering 69.6% of sequence.
  
  
 0.455
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.439
plsC
1-acyl-sn-glycerol-3-phosphate acyltransferase; COG0204; expression validated by proteogenomic mapping: 11 unique peptides covering 33.3% of sequence.
   
 
 0.401
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.