Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bioF8-amino-7-oxononanoate synthase; COG0156; expression validated by proteogenomic mapping: 63 unique peptides covering 80.7% of sequence. (398 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.939
wcaG
NAD-dependent nucleoside-diphosphate-sugar epimerase; COG0451; expression validated by proteogenomic mapping: 48 unique peptides covering 79.4% of sequence.
  
 
 0.898
acpP
Acyl carrier protein; COG0236; expression validated by proteogenomic mapping: 7 unique peptides covering 69.6% of sequence.
  
 
 0.799
coaE
Hypothetical dephospho-CoA kinase; COG0237; expression not validated.
  
  
 0.646
coaD
Putative phosphopantetheine adenylyltransferase; COG0669; expression validated by proteogenomic mapping: 4 unique peptides covering 32.4% of sequence.
     
 0.603
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.572
ssb
Single strand binding protein; COG0629; expression validated by proteogenomic mapping: 13 unique peptides covering 44% of sequence.
    
  0.523
pdhB
Pyruvate dehydrogenase E1 component beta subunit; COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence.
  
 
  0.519
metK
S-adenosylmethionine synthetase; COG0192; expression validated by proteogenomic mapping: 23 unique peptides covering 50% of sequence; Belongs to the AdoMet synthase family.
   
 
 0.506
lonA
ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
   
 
 0.500
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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