Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (370 aa)    
Predicted Functional Partners:
pdhD-2
Pyruvate dehydrogenase E3 component dihydrolipoamide dehydrogenase; COG1249; expression validated by proteogenomic mapping: 88 unique peptides covering 75% of sequence.
  
 0.999
pdhB
Pyruvate dehydrogenase E1 component beta subunit; COG0022; expression validated by proteogenomic mapping: 56 unique peptides covering 71.8% of sequence.
 0.999
pdhC
Pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 78 unique peptides covering 80.1% of sequence.
  
 0.993
pdhC-2
Truncated pyruvate dehydrogenase E2 component dihydrolipoamide acetyltransferase; COG0508; expression validated by proteogenomic mapping: 29 unique peptides covering 69.5% of sequence.
  
 0.993
pyk
Pyruvate kinase; COG0469; expression validated by proteogenomic mapping: 72 unique peptides covering 78.9% of sequence; Belongs to the pyruvate kinase family.
  
 
 0.935
pdhD
Dihydrolipoamide dehydrogenase (pyruvate dehydrogenase complex); COG1249; expression validated by proteogenomic mapping: 25 unique peptides covering 40% of sequence.
  
 
 0.934
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.932
fba
Fructose-bisphosphate aldolase; COG0191; expression validated by proteogenomic mapping: 45 unique peptides covering 85.2% of sequence.
  
 
 0.876
tktA
Transketolase; COG0021; expression validated by proteogenomic mapping: 83 unique peptides covering 74.1% of sequence; Belongs to the transketolase family.
  
 
 0.872
pgi
Glucose-6-phosphate isomerase; COG0166; expression validated by proteogenomic mapping: 41 unique peptides covering 65.1% of sequence.
    
 0.861
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
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