Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ribARiboflavin biosynthesis protein; COG0807; expression validated by proteogenomic mapping: 9 unique peptides covering 20.4% of sequence. (343 aa)    
Predicted Functional Partners:
MMOB2880
Expressed protein; COG0327; expression validated by proteogenomic mapping: 3 unique peptides covering 15% of sequence.
    
  0.902
rpsB
30S ribosomal protein s2; COG0052; expression validated by proteogenomic mapping: 52 unique peptides covering 72.3% of sequence; Belongs to the universal ribosomal protein uS2 family.
  
  
 0.812
udgA
UDP-glucose dehydrogenase; COG1004; expression validated by proteogenomic mapping: 8 unique peptides covering 25% of sequence.
  
  
 0.796
MMOB5990
Hypothetical protein; Expression not validated.
  
    0.778
MMOB5980
Expressed protein; Expression validated by proteogenomic mapping: 7 unique peptides covering 11.3% of sequence.
       0.773
MMOB6000
Hypothetical protein; Expression not validated.
       0.773
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.600
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.593
wcaG
NAD-dependent nucleoside-diphosphate-sugar epimerase; COG0451; expression validated by proteogenomic mapping: 48 unique peptides covering 79.4% of sequence.
  
 
 0.586
ybeY
Putative metal binding protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
 
 0.574
Your Current Organism:
Mycoplasma mobile
NCBI taxonomy Id: 267748
Other names: M. mobile 163K, Mycoplasma mobile 163K, Mycoplasma mobile str. 163K, Mycoplasma mobile strain 163K
Server load: low (16%) [HD]