STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnPPutative cytoplasmic protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (93 aa)    
Predicted Functional Partners:
ADINL_1218
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
     
 0.953
ADINL_0393
Putative hydrolase.
     
  0.952
ADINL_0756
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
     
  0.952
ADINL_0759
Xanthine dehydrogenase, molybdenum binding subunit.
     
  0.952
ADINL_0760
Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A.
     
  0.952
ADINL_1984
Hypoxanthine-guanine phosphoribosyltransferase.
     
  0.952
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
  0.952
gpt
Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
  0.936
ADINL_2226
Decarboxylase family protein.
  
  
  0.922
ADINL_1341
5'-nucleotidase.
     
  0.870
Your Current Organism:
Nitrincola lacisaponensis
NCBI taxonomy Id: 267850
Other names: ATCC BAA-920, DSM 16316, N. lacisaponensis, Nitrincola lacisaponensis Dimitriu et al. 2005, strain 4CA
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