STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADINL_1751Proline dehydrogenase (Proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1039 aa)    
Predicted Functional Partners:
ADINL_1750
Proline dehydrogenase (Proline oxidase); Overlaps CDS with the same product name; Delta-1-pyrroline-5-carboxylate dehydrogenase.
  
  0.981
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.978
ADINL_3094
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.963
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.951
ADINL_1891
Serine phosphatase RsbU, regulator of sigma subunit.
  
  
 0.948
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
    
 0.945
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.945
ADINL_1741
Glutamate synthase [NADPH] large chain.
  
 
 0.944
ADINL_2310
NAD-specific glutamate dehydrogenase, large form.
  
  
 0.942
purL
Phosphoribosylformylglycinamidine synthase, synthetase subunit; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
    
 0.940
Your Current Organism:
Nitrincola lacisaponensis
NCBI taxonomy Id: 267850
Other names: ATCC BAA-920, DSM 16316, N. lacisaponensis, Nitrincola lacisaponensis Dimitriu et al. 2005, strain 4CA
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