Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (358 aa)    
Predicted Functional Partners:
KGE18707.1
Dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
uxaC
Glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
KGE18221.1
2-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
KGE18220.1
Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.917
KGE17134.1
Converts D-mannonate to D-mannuronate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.915
KGE18709.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.883
KGE19857.1
6-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.867
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.859
KGE16668.1
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.848
KGE16723.1
Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family.
     
  0.848
Your Current Organism:
Paenibacillus wynnii
NCBI taxonomy Id: 268407
Other names: CIP 108306, DSM 18334, LMG 22176, LMG:22176, P. wynnii, Paenibacillus wynnii Rodriguez-Diaz et al. 2005
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