| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KGE19020.1 | KGE20389.1 | PWYN_06390 | PWYN_14345 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| KGE19020.1 | deoC | PWYN_06390 | PWYN_02235 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.929 |
| KGE19020.1 | pdxS | PWYN_06390 | PWYN_11600 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.899 |
| KGE19020.1 | rbsK | PWYN_06390 | PWYN_08050 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.913 |
| KGE19020.1 | rpiA | PWYN_06390 | PWYN_18890 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.968 |
| KGE19307.1 | rbsA-2 | PWYN_08030 | PWYN_08040 | D-ribose transporter subunit RbsB; Periplasmic substrate-binding component of the ATP-dependent ribose transport system; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-ribose transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. | 0.970 |
| KGE19307.1 | rbsC | PWYN_08030 | PWYN_08035 | D-ribose transporter subunit RbsB; Periplasmic substrate-binding component of the ATP-dependent ribose transport system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose ABC transporter permease; Functions to transport ribose at high affinity; forms a complex with RbsA2C2B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. | 0.998 |
| KGE19307.1 | rbsD | PWYN_08030 | PWYN_08045 | D-ribose transporter subunit RbsB; Periplasmic substrate-binding component of the ATP-dependent ribose transport system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. | 0.975 |
| KGE19307.1 | rbsK | PWYN_08030 | PWYN_08050 | D-ribose transporter subunit RbsB; Periplasmic substrate-binding component of the ATP-dependent ribose transport system; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.931 |
| KGE20389.1 | KGE19020.1 | PWYN_14345 | PWYN_06390 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.913 |
| KGE20389.1 | deoC | PWYN_14345 | PWYN_02235 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.964 |
| KGE20389.1 | rbsK | PWYN_14345 | PWYN_08050 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.902 |
| KGE20389.1 | rpiA | PWYN_14345 | PWYN_18890 | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. | 0.909 |
| deoC | KGE19020.1 | PWYN_02235 | PWYN_06390 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.929 |
| deoC | KGE20389.1 | PWYN_02235 | PWYN_14345 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.964 |
| deoC | rbsK | PWYN_02235 | PWYN_08050 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.967 |
| pdxS | KGE19020.1 | PWYN_11600 | PWYN_06390 | Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.899 |
| pdxS | pdxT | PWYN_11600 | PWYN_11595 | Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.999 |
| pdxS | rbsK | PWYN_11600 | PWYN_08050 | Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.896 |
| pdxT | pdxS | PWYN_11595 | PWYN_11600 | Glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | Pyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.999 |
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