Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KGE16368.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)    
Predicted Functional Partners:
KGE18603.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.861
KGE18592.1
Histidine kinase; C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.773
KGE16369.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.769
KGE20967.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.610
KGE18964.1
Polya polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.477
KGE16370.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.468
KGE19736.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.461
KGE16367.1
Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.405
Your Current Organism:
Paenibacillus wynnii
NCBI taxonomy Id: 268407
Other names: CIP 108306, DSM 18334, LMG 22176, LMG:22176, P. wynnii, Paenibacillus wynnii Rodriguez-Diaz et al. 2005
Server load: low (14%) [HD]