node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGE16296.1 | KGE16297.1 | PWYN_16205 | PWYN_16210 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KGE16296.1 | KGE16846.1 | PWYN_16205 | PWYN_19380 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
KGE16296.1 | KGE18380.1 | PWYN_16205 | PWYN_28130 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein hesA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.784 |
KGE16296.1 | guaB | PWYN_16205 | PWYN_11610 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.532 |
KGE16296.1 | thiC | PWYN_16205 | PWYN_08375 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.956 |
KGE16296.1 | thiG | PWYN_16205 | PWYN_16215 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
KGE16296.1 | thiM | PWYN_16205 | PWYN_19385 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.992 |
KGE16297.1 | KGE16296.1 | PWYN_16210 | PWYN_16205 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.987 |
KGE16297.1 | KGE16846.1 | PWYN_16210 | PWYN_19380 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
KGE16297.1 | KGE18380.1 | PWYN_16210 | PWYN_28130 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein hesA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
KGE16297.1 | thiC | PWYN_16210 | PWYN_08375 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.861 |
KGE16297.1 | thiG | PWYN_16210 | PWYN_16215 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.998 |
KGE16297.1 | thiM | PWYN_16210 | PWYN_19385 | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.729 |
KGE16846.1 | KGE16296.1 | PWYN_19380 | PWYN_16205 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
KGE16846.1 | KGE16297.1 | PWYN_19380 | PWYN_16210 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.940 |
KGE16846.1 | KGE16848.1 | PWYN_19380 | PWYN_19390 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.780 |
KGE16846.1 | KGE16849.1 | PWYN_19380 | PWYN_19395 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.780 |
KGE16846.1 | KGE16850.1 | PWYN_19380 | PWYN_19400 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.780 |
KGE16846.1 | KGE18380.1 | PWYN_19380 | PWYN_28130 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein hesA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.702 |
KGE16846.1 | guaB | PWYN_19380 | PWYN_11610 | Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.721 |