Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KGE17422.12-dehydropantoate 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.934
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.930
KGE18126.1
Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
     
  0.848
KGE19821.1
Ketopantoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.742
KGE17423.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.618
KGE16586.1
Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
    
  0.443
KGE16876.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.430
KGE18629.1
1,4-beta-xylanase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.429
Your Current Organism:
Paenibacillus wynnii
NCBI taxonomy Id: 268407
Other names: CIP 108306, DSM 18334, LMG 22176, LMG:22176, P. wynnii, Paenibacillus wynnii Rodriguez-Diaz et al. 2005
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