N-3 protein (Trichinella papuae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

N-3

Neurogenic locus Notch protein. (315 aa)

Predicted Functional Partners:

lrk-1

0.874

Su(H)

0.792

unc-89-2

0.783

unc-89-3

0.783

dvl3

0.771

TONSL

0.717

PTK7

0.706

sel-12

0.663

Ncstn

0.650

ADAM10

0.633

Your Current Organism:

Trichinella papuae

NCBI taxonomy Id: 268474
Other names: T. papuae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	N-3	A0A0V1MIC9	A0A0V1N7A8	Disintegrin and metalloproteinase domain-containing protein 10.	Neurogenic locus Notch protein.	0.633
ADAM10	Ncstn	A0A0V1MIC9	A0A0V1MD21	Disintegrin and metalloproteinase domain-containing protein 10.	Nicastrin.	0.595
ADAM10	sel-12	A0A0V1MIC9	A0A0V1N7K9	Disintegrin and metalloproteinase domain-containing protein 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.573
N-3	ADAM10	A0A0V1N7A8	A0A0V1MIC9	Neurogenic locus Notch protein.	Disintegrin and metalloproteinase domain-containing protein 10.	0.633
N-3	Ncstn	A0A0V1N7A8	A0A0V1MD21	Neurogenic locus Notch protein.	Nicastrin.	0.650
N-3	PTK7	A0A0V1N7A8	A0A0V1MQF7	Neurogenic locus Notch protein.	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.706
N-3	Su(H)	A0A0V1N7A8	A0A0V1MSC0	Neurogenic locus Notch protein.	Suppressor of hairless protein.	0.792
N-3	TONSL	A0A0V1N7A8	A0A0V1MB97	Neurogenic locus Notch protein.	Tonsoku-like protein.	0.717
N-3	dvl3	A0A0V1N7A8	A0A0V1M2F0	Neurogenic locus Notch protein.	Segment polarity protein dishevelled-like protein DVL-3.	0.771
N-3	lrk-1	A0A0V1N7A8	A0A0V1M649	Neurogenic locus Notch protein.	Leucine-rich repeat serine/threonine-protein kinase 1.	0.874
N-3	sel-12	A0A0V1N7A8	A0A0V1N7K9	Neurogenic locus Notch protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.663
N-3	unc-89-2	A0A0V1N7A8	A0A0V1MLY3	Neurogenic locus Notch protein.	Muscle M-line assembly protein unc-89.	0.783
N-3	unc-89-3	A0A0V1N7A8	A0A0V1MMJ8	Neurogenic locus Notch protein.	Muscle M-line assembly protein unc-89.	0.783
Ncstn	ADAM10	A0A0V1MD21	A0A0V1MIC9	Nicastrin.	Disintegrin and metalloproteinase domain-containing protein 10.	0.595
Ncstn	N-3	A0A0V1MD21	A0A0V1N7A8	Nicastrin.	Neurogenic locus Notch protein.	0.650
Ncstn	lrk-1	A0A0V1MD21	A0A0V1M649	Nicastrin.	Leucine-rich repeat serine/threonine-protein kinase 1.	0.507
Ncstn	sel-12	A0A0V1MD21	A0A0V1N7K9	Nicastrin.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.994
PTK7	N-3	A0A0V1MQF7	A0A0V1N7A8	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Neurogenic locus Notch protein.	0.706
PTK7	TONSL	A0A0V1MQF7	A0A0V1MB97	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tonsoku-like protein.	0.838
PTK7	dvl3	A0A0V1MQF7	A0A0V1M2F0	Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Segment polarity protein dishevelled-like protein DVL-3.	0.792