STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (151 aa)    
Predicted Functional Partners:
Amt
Aminomethyltransferase, mitochondrial.
 
 0.979
Gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.978
PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial.
  
 0.947
mel-32
Serine hydroxymethyltransferase.
  
 
 0.932
Mthfr
Putative methylenetetrahydrofolate reductase.
    
 0.867
lipt2
Putative lipoyltransferase 2, mitochondrial.
   
 0.849
TYMS
Thymidylate synthase.
    
 0.836
GART
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
  
 0.831
T11_3591
Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
   
 0.826
DHFR
Dihydrofolate reductase.
    
 0.824
Your Current Organism:
Trichinella zimbabwensis
NCBI taxonomy Id: 268475
Other names: T. zimbabwensis, Trichinella zimbabwensis Pozio, Foggin, Marucci, La-Rosa, Sacchi, Corona, Rossi & Mukaratirwa, 2002
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.