tmem208 protein (Trichinella zimbabwensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tmem208

Transmembrane protein. (102 aa)

Predicted Functional Partners:

Atg9a

0.973

asna1

0.636

Sec61a2

0.574

T11_9883

0.566

Wdfy3

0.563

tsg

0.522

GET4

0.485

BPNT1

0.482

RAD51D

0.470

RAD51

0.470

Your Current Organism:

Trichinella zimbabwensis

NCBI taxonomy Id: 268475
Other names: T. zimbabwensis, Trichinella zimbabwensis Pozio, Foggin, Marucci, La-Rosa, Sacchi, Corona, Rossi & Mukaratirwa, 2002

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atg9a	tmem208	A0A0V1HYD2	A0A0V1H3Q1	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Transmembrane protein.	0.973
BPNT1	tmem208	A0A0V1HGE6	A0A0V1H3Q1	3'(2'),5'-bisphosphate nucleotidase 1.	Transmembrane protein.	0.482
GET4	Sec61a2	A0A0V1HB37	A0A0V1I4F0	Golgi to ER traffic protein 4-like protein.	Protein transport protein Sec61 subunit alpha isoform 2.	0.422
GET4	asna1	A0A0V1HB37	A0A0V1HGQ6	Golgi to ER traffic protein 4-like protein.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.998
GET4	tmem208	A0A0V1HB37	A0A0V1H3Q1	Golgi to ER traffic protein 4-like protein.	Transmembrane protein.	0.485
RAD51	T11_9883	A0A0V1HUZ9	A0A0V1HZU2	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	Uncharacterized protein.	0.991
RAD51	tmem208	A0A0V1HUZ9	A0A0V1H3Q1	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	Transmembrane protein.	0.470
RAD51D	T11_9883	A0A0V1HBH2	A0A0V1HZU2	DNA repair protein RAD51-like protein 4.	Uncharacterized protein.	0.967
RAD51D	tmem208	A0A0V1HBH2	A0A0V1H3Q1	DNA repair protein RAD51-like protein 4.	Transmembrane protein.	0.470
Sec61a2	GET4	A0A0V1I4F0	A0A0V1HB37	Protein transport protein Sec61 subunit alpha isoform 2.	Golgi to ER traffic protein 4-like protein.	0.422
Sec61a2	asna1	A0A0V1I4F0	A0A0V1HGQ6	Protein transport protein Sec61 subunit alpha isoform 2.	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	0.659
Sec61a2	tmem208	A0A0V1I4F0	A0A0V1H3Q1	Protein transport protein Sec61 subunit alpha isoform 2.	Transmembrane protein.	0.574
T11_9883	RAD51	A0A0V1HZU2	A0A0V1HUZ9	Uncharacterized protein.	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily.	0.991
T11_9883	RAD51D	A0A0V1HZU2	A0A0V1HBH2	Uncharacterized protein.	DNA repair protein RAD51-like protein 4.	0.967
T11_9883	tmem208	A0A0V1HZU2	A0A0V1H3Q1	Uncharacterized protein.	Transmembrane protein.	0.566
Wdfy3	tmem208	A0A0V1HZT2	A0A0V1H3Q1	WD repeat and FYVE domain-containing protein 3.	Transmembrane protein.	0.563
asna1	GET4	A0A0V1HGQ6	A0A0V1HB37	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Golgi to ER traffic protein 4-like protein.	0.998
asna1	Sec61a2	A0A0V1HGQ6	A0A0V1I4F0	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Protein transport protein Sec61 subunit alpha isoform 2.	0.659
asna1	tmem208	A0A0V1HGQ6	A0A0V1H3Q1	ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]	Transmembrane protein.	0.636
tmem208	Atg9a	A0A0V1H3Q1	A0A0V1HYD2	Transmembrane protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.973