Cdk1 protein (Trichinella zimbabwensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Cdk1

Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (319 aa)

Predicted Functional Partners:

T11_7063

0.940

wee-1.3

0.917

Cdc6

0.915

plk1

0.889

Fzr1

0.880

Cdc20

0.880

CCND2

0.879

ccnb2

0.867

T11_16228

0.846

CycB3

0.846

Your Current Organism:

Trichinella zimbabwensis

NCBI taxonomy Id: 268475
Other names: T. zimbabwensis, Trichinella zimbabwensis Pozio, Foggin, Marucci, La-Rosa, Sacchi, Corona, Rossi & Mukaratirwa, 2002

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCND2	Cdc20	A0A0V1I172	A0A0V1H5D3	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Cell division cycle protein 20-like protein.	0.504
CCND2	Cdk1	A0A0V1I172	A0A0V1HIC0	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.879
CCND2	Fzr1	A0A0V1I172	A0A0V1GVL2	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Fizzy-related-like protein.	0.504
CCND2	T11_7063	A0A0V1I172	A0A0V1GXA0	G1/S-specific cyclin-D2; Belongs to the cyclin family.	G2/mitotic-specific cyclin; Belongs to the cyclin family.	0.595
CCND2	wee-1.3	A0A0V1I172	A0A0V1HBP0	G1/S-specific cyclin-D2; Belongs to the cyclin family.	Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase wee-1.3.	0.547
Cdc20	CCND2	A0A0V1H5D3	A0A0V1I172	Cell division cycle protein 20-like protein.	G1/S-specific cyclin-D2; Belongs to the cyclin family.	0.504
Cdc20	Cdc6	A0A0V1H5D3	A0A0V1HFY6	Cell division cycle protein 20-like protein.	Cell division control protein 6-like protein.	0.844
Cdc20	Cdk1	A0A0V1H5D3	A0A0V1HIC0	Cell division cycle protein 20-like protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.880
Cdc20	CycB3	A0A0V1H5D3	A0A0V1HAP8	Cell division cycle protein 20-like protein.	G2/mitotic-specific cyclin-B3; Belongs to the cyclin family.	0.887
Cdc20	T11_16228	A0A0V1H5D3	A0A0V1HA07	Cell division cycle protein 20-like protein.	Uncharacterized protein.	0.887
Cdc20	T11_7063	A0A0V1H5D3	A0A0V1GXA0	Cell division cycle protein 20-like protein.	G2/mitotic-specific cyclin; Belongs to the cyclin family.	0.955
Cdc20	ccnb2	A0A0V1H5D3	A0A0V1GZ87	Cell division cycle protein 20-like protein.	G2/mitotic-specific cyclin-B2; Belongs to the cyclin family.	0.887
Cdc20	plk1	A0A0V1H5D3	A0A0V1HZM5	Cell division cycle protein 20-like protein.	Serine/threonine-protein kinase PLK.	0.958
Cdc20	wee-1.3	A0A0V1H5D3	A0A0V1HBP0	Cell division cycle protein 20-like protein.	Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase wee-1.3.	0.686
Cdc6	Cdc20	A0A0V1HFY6	A0A0V1H5D3	Cell division control protein 6-like protein.	Cell division cycle protein 20-like protein.	0.844
Cdc6	Cdk1	A0A0V1HFY6	A0A0V1HIC0	Cell division control protein 6-like protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.915
Cdc6	CycB3	A0A0V1HFY6	A0A0V1HAP8	Cell division control protein 6-like protein.	G2/mitotic-specific cyclin-B3; Belongs to the cyclin family.	0.816
Cdc6	Fzr1	A0A0V1HFY6	A0A0V1GVL2	Cell division control protein 6-like protein.	Fizzy-related-like protein.	0.844
Cdc6	T11_16228	A0A0V1HFY6	A0A0V1HA07	Cell division control protein 6-like protein.	Uncharacterized protein.	0.816
Cdc6	T11_7063	A0A0V1HFY6	A0A0V1GXA0	Cell division control protein 6-like protein.	G2/mitotic-specific cyclin; Belongs to the cyclin family.	0.992