STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ME1Malic enzyme. (602 aa)    
Predicted Functional Partners:
fum-1
Putative fumarate hydratase, mitochondrial.
  
 
 0.967
MRRF
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.942
T11_216
Citrate synthase; Belongs to the citrate synthase family.
  
 0.918
AcCoAS
Acetyl-coenzyme A synthetase.
  
 0.897
pyc-1
Pyruvate carboxylase 1.
   
 0.883
ilvbl
Acetolactate synthase-like protein; Belongs to the TPP enzyme family.
  
 
 0.861
T11_13950
RING-type domain-containing protein.
  
 0.849
Ankrd49
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.841
Afmid
Kynurenine formamidase.
    
 0.839
PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial.
  
 
 0.839
Your Current Organism:
Trichinella zimbabwensis
NCBI taxonomy Id: 268475
Other names: T. zimbabwensis, Trichinella zimbabwensis Pozio, Foggin, Marucci, La-Rosa, Sacchi, Corona, Rossi & Mukaratirwa, 2002
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