STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pabp2-2Polyadenylate-binding protein 2. (241 aa)    
Predicted Functional Partners:
Ranbp2
E3 SUMO-protein ligase RanBP2.
   
 
  0.975
Ranbp1
Ran-specific GTPase-activating protein.
   
 
  0.975
ACIN1
Apoptotic chromatin condensation inducer in the nucleus.
   
 0.892
Prdm13
Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.
   
 0.866
Bin1
Histone deacetylase complex subunit SAP18.
   
 0.857
Ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.
  
 
 0.853
Eif4a3
Eukaryotic initiation factor 4A-III.
   
 0.851
UPF2
Regulator of nonsense transcripts 2.
    
 0.831
Fip1l1
Pre-mRNA 3'-end-processing factor FIP1.
    
 0.813
tsu
RNA-binding protein 8A.
    
 0.809
Your Current Organism:
Trichinella zimbabwensis
NCBI taxonomy Id: 268475
Other names: T. zimbabwensis, Trichinella zimbabwensis Pozio, Foggin, Marucci, La-Rosa, Sacchi, Corona, Rossi & Mukaratirwa, 2002
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.